MovDisordV3, Main, Exploration, bibRecord, 000198

L-dopa increases α-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro.

Identifieur interne : 000198 ( Main/Exploration ); précédent : 000197; suivant : 000199

L-dopa increases α-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro.

Auteurs : Ina Schmitt [Allemagne] ; Oliver Kaut [Allemagne] ; Hassan Khazneh [Allemagne] ; Laura Deboni [Allemagne] ; Ashar Ahmad [Allemagne] ; Daniela Berg [Allemagne] ; Christine Klein [Allemagne] ; Holger Fröhlich [Allemagne] ; Ullrich Wüllner [Allemagne]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:26173746

Abstract

Increasing gene dosages of α-synuclein induce familial Parkinson's disease (PD); thus, the hypothesis has been put forward that regulation of gene expression, in particular altered α-synuclein gene methylation, might be associated with sporadic PD and could be used as a biological marker.

DOI: 10.1002/mds.26319
PubMed: 26173746

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Increasing gene dosages of α-synuclein induce familial Parkinson's disease (PD); thus, the hypothesis has been put forward that regulation of gene expression, in particular altered α-synuclein gene methylation, might be associated with sporadic PD and could be used as a biological marker.</div>
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Movement Disorders (revue)

L-dopa increases α-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro.

L-dopa increases α-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro.

Source :

Abstract

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